New paper out in Nature Biotechnology: Phage therapy for Tomato wilt
Me and Daniel Jeffares will be guest editing a special issue in MDPI Pathogens entitled: "Ecology, Evolution and genomics of R. solanacearum plant pathogenic bacterium". Information and instructions how to submit a manuscript available HERE!
Thanks for everyone who came to listen my talk in ESEB 2019 symposium 24: 'Microbial evolution under biotic stress'
Thank you for visiting our symposium 'Microbial Evolution in Complex Environments' and thanks for our
Invited speakers Jo Fothergill and Angus Buckling for great presentations!
Thank you for coming to listen my talk in Ireland
Thank you for visiting our symposium 13: Pathogen evolution during chronic infections. See you in ESEB 2019!
Read our opinion piece about phage therapy here:
Silk route to the acceptance and re-implementation of phage therapy
Read my blog about phage therapy @ Conversation:
Soviet-era treatment could be the new weapon in the war against antibiotic resistance
We are interested in eco-evolutionary dynamics of species interactions in multi-trophic communities. We are specifically focused on plant rhizosphere and human lung microbiomes and how interactions within these microbial communities affect the fitness and survival of associated host organisms. Elucidating these processes is especially important for understanding bacterial disease dynamics in agricultural and medical contexts and developing new ways to control infections. Moreover, we are interested in how the rapid evolution of species interactions might feedback and change the composition, stability and the functioning of microbial ecosystems.
We use two main study systems in our research. First, we use model cystic fibrosis lung microbiome to focus on understanding how the evolution of Pseudomonas aeruginosa bacterial pathogen is shaped by sub-inhibitory antibiotic concentrations, other co-occurring bacteria and lytic phages. Second, we use a tomato rhizosphere microbiome model to study bacteria-phage-plant interactions in soil focusing on Ralstonia solanacearum plant pathogenic bacterium (a causative agent of bacterial wilt disease). We combine experimental evolution with environmental and clinical sampling, field and greenhouse experiments, genome sequencing and bioinformatic analysis and work with various microbes including bacteria, phages, protists.
Our main interests include
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Lecturer in Evolutionary Biology
Department of Biology (L012)
University of York
Honorary Guest Professor
Nanjing Agricultural University
Associate Editor in: